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Mitochondrial permeability transition pore and calcium handling

The opening of the a large conductance channel in the inner mitochondrial membrane, known as the mitochondrial permeability transition pore (MPTP) has been shown to be a primary mediator of cell death in heart subjected to ischemia-reperfusion injury. Inhibitors of the MPTP have been shown to reduce...

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Main Authors: Wong, Renee, Steenbergen, Charles, Murphy, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461591/
https://ncbi.nlm.nih.gov/pubmed/22057571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-382-0_15
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