Phosphorus-containing inhibitors of angiotensin-converting enzyme.

Several phosphonamides, phosphoramides, and phosphates having the general structure R-Y-P(O)(OH)-X-CH(CH3)-CO-Pro have been synthesized and tested for inhibition of angiotensin-converting enzyme (dipeptidyl carboxypeptidase; peptidyl-dipeptide hydrolase, EC 3.4.15.1). Inhibition was found to depend...

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Autors principals: Thorsett, E D, Harris, E E, Peterson, E R, Greenlee, W J, Patchett, A A, Ulm, E H, Vassil, T C
Format: Artigo
Idioma:Inglês
Publicat: 1982
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC346153/
https://ncbi.nlm.nih.gov/pubmed/6285369
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