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Group I PAKs function downstream of Rac to promote podosome invasion during myoblast fusion in vivo

The p21-activated kinases (PAKs) play essential roles in diverse cellular processes and are required for cell proliferation, apoptosis, polarity establishment, migration, and cell shape changes. Here, we have identified a novel function for the group I PAKs in cell–cell fusion. We show that the two...

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Autors principals: Duan, Rui, Jin, Peng, Luo, Fengbao, Zhang, Guofeng, Anderson, Nathan, Chen, Elizabeth H.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461515/
https://ncbi.nlm.nih.gov/pubmed/23007650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201204065
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