5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress

BACKGROUND: Cardiotoxicity is a major complication of anticancer drugs, including anthracyclines and 5-fluorouracil(5-FU) and it can have detrimental effects both in patients and workers involved in the preparation of chemotherapy. METHODS: Specifically, we have assessed the effects of increasing co...

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Bibliografiske detaljer
Main Authors: Lamberti, Monica, Porto, Stefania, Marra, Monica, Zappavigna, Silvia, Grimaldi, Anna, Feola, Daniela, Pesce, Delia, Naviglio, Silvio, Spina, Annamaria, Sannolo, Nicola, Caraglia, Michele
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461434/
https://ncbi.nlm.nih.gov/pubmed/22812382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-60
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