RecQL4 cytoplasmic localization: implications in mitochondrial DNA oxidative damage repair

RecQL4, one of the five human RecQ helicases, is crucial for genomic stability and RecQL4 when mutated leads to premature aging phenotypes in humans. Unlike other human RecQ helicases, RecQL4 is found both in the nucleus and the cytoplasm. While the nuclear localization signal (NLS) and the retentio...

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Main Authors: Chi, Zhenfen, Nie, Linghu, Peng, Zhao, Yang, Qiong, Yang, Kuan, Tao, Jiahai, Mi, Yang, Fang, Xiangdong, Balajee, Adayabalam S., Zhao, Yongliang
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461334/
https://ncbi.nlm.nih.gov/pubmed/22824301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2012.07.016
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