Replication and Meta-analysis of the Gene-Environment Interaction between Body Mass Index and the Interleukin-6 Promoter Polymorphism with Higher Insulin Resistance

OBJECTIVE: Insulin resistance (IR) is a complex disorder caused by an interplay of both genetic and environmental factors. Recent studies identified a significant interaction between body mass index (BMI) and the rs1800795 polymorphism of the Interleukin-6 (IL-6) gene that influences both IR and ons...

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Main Authors: Underwood, Patricia C., Chamarthi, Bindu, Williams, Jonathan S., Sun, Bei, Vaidya, Anand, Raby, Benjamin A., Lasky-Su, Jessica, Hopkins, Paul N., Adler, Gail K., Williams, Gordon H.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461261/
https://ncbi.nlm.nih.gov/pubmed/22075267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2011.09.018
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