Different Polymorphisms of the Mineralocorticoid Receptor Gene Are Associated with either Glucocorticoid or Mineralocorticoid Levels in Hypertension

OBJECTIVE: Both aldosterone and cortisol can activate the mineralocorticoid receptor (MR). Polymorphisms in the MR gene have been inconsistently shown to be associated with risk of hypertension and aldosterone and cortisol levels. The purpose of this project was to investigate the association of MR...

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Detalhes bibliográficos
Main Authors: Sun, Bei, Chamarthi, Bindu, Williams, Jonathan S., Krug, Alexander W., Lasky-Su, Jessica, Raby, Benjamin A., Hopkins, Paul N., Jeunemaitre, Xavier, Ferri, Claudio, Williams, Gordon H.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
JCEM Online: Advances in Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431565/
https://ncbi.nlm.nih.gov/pubmed/22723323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-1486
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