Different Polymorphisms of the Mineralocorticoid Receptor Gene Are Associated with either Glucocorticoid or Mineralocorticoid Levels in Hypertension

OBJECTIVE: Both aldosterone and cortisol can activate the mineralocorticoid receptor (MR). Polymorphisms in the MR gene have been inconsistently shown to be associated with risk of hypertension and aldosterone and cortisol levels. The purpose of this project was to investigate the association of MR...

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Autors principals: Sun, Bei, Chamarthi, Bindu, Williams, Jonathan S., Krug, Alexander W., Lasky-Su, Jessica, Raby, Benjamin A., Hopkins, Paul N., Jeunemaitre, Xavier, Ferri, Claudio, Williams, Gordon H.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2012
Matèries:
JCEM Online: Advances in Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431565/
https://ncbi.nlm.nih.gov/pubmed/22723323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-1486
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