POLYMORPHISMS IN THE SERUM- AND GLUCOCORTICOID-INDUCIBLE KINASE 1 GENE ARE ASSOCIATED WITH BLOOD PRESSURE AND RENIN RESPONSE TO DIETARY SALT INTAKE

Serum- and glucocorticoid-inducible kinase 1 (SGK1) plays a central role in epithelial sodium channel (ENaC)-dependent Na(+) transport in the distal nephron. We hypothesized that SGK1 gene variants may contribute to the effect of dietary salt intake on BP in humans with hypertension, and consequenti...

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Detalhes bibliográficos
Main Authors: Rao, Ajay D, Sun, Bei, Saxena, Aditi, Hopkins, Paul N, Jeunemaitre, Xavier, Brown, Nancy J, Adler, Gail K, Williams, Jonathan S
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463709/
https://ncbi.nlm.nih.gov/pubmed/22648267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhh.2012.22
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