Immunity to Sand Fly Salivary Protein LJM11 Modulates Host Response to Vector-Transmitted Leishmania Conferring Ulcer-Free Protection

Leishmania vaccines that protect against needle challenge fail against the potency of a Leishmania-infected sand fly transmission. Here, we demonstrate that intradermal immunization of mice with 500 ng of the sand fly salivary recombinant protein LJM11 (rLJM11) from Lutzomyia longipalpis, in the abs...

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Detalhes bibliográficos
Main Authors: Gomes, Regis, Oliveira, Fabiano, Teixeira, Clarissa, Meneses, Claudio, Gilmore, Dana C, Elnaiem, Dia-Eldin, Kamhawi, Shaden, Valenzuela, Jesus G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461249/
https://ncbi.nlm.nih.gov/pubmed/22739793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.205
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