Sand Fly Salivary Proteins Induce Strong Cellular Immunity in a Natural Reservoir of Visceral Leishmaniasis with Adverse Consequences for Leishmania

Immunity to a sand fly salivary protein protects against visceral leishmaniasis (VL) in hamsters. This protection was associated with the development of cellular immunity in the form of a delayed-type hypersensitivity response and the presence of IFN-γ at the site of sand fly bites. To date, there a...

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Main Authors: Collin, Nicolas, Gomes, Regis, Teixeira, Clarissa, Cheng, Lily, Laughinghouse, Andre, Ward, Jerrold M., Elnaiem, Dia-Eldin, Fischer, Laurent, Valenzuela, Jesus G., Kamhawi, Shaden
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677456/
https://ncbi.nlm.nih.gov/pubmed/19461875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000441
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