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Detection of hyaluronidase activity using fluorescein labeled hyaluronic acid and fluorescence correlation spectroscopy

The over-expression of hyaluronidase has been observed in many types of cancer, suggesting that it may have utility for diagnosis. Here we present a technique for the detection of hyaluronidase using Fluorescence Correlation Spectroscopy (FCS). Hyaluronan macromolecules (HAs) have been heavily label...

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Detalhes bibliográficos
Main Authors: Rich, Ryan M., Mummert, Mark, Foldes-Papp, Zeno, Gryczynski, Zygmunt, Borejdo, Julian, Gryczynski, Ignacy, Fudala, Rafal
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461185/
https://ncbi.nlm.nih.gov/pubmed/23018154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jphotobiol.2012.07.007
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