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Lifetime-based sensing of the hyaluronidase using fluorescein labeled hyaluronic acid

In this report we propose a lifetime-based sensing (LBS) for the detection of hyaluronidase (HA-ase). First, we heavily label hyaluronan macromolecules (HA) with fluorescein amine. The fluorescein labeled HA (HA-Fl) has a weak fluorescence and short fluorescence lifetime due to an efficient self-que...

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書誌詳細
主要な著者: Fudala, Rafal, Mummert, Mark E., Gryczynski, Zygmunt, Rich, Ryan, Borejdo, Julian, Gryczynski, Ignacy
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242895/
https://ncbi.nlm.nih.gov/pubmed/22082776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jphotobiol.2011.10.005
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