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Complementation of the defects of DNA synthesis in irradiated and unirradiated ataxia-telangiectasia cells.

Mutant subtypes in the human genetic disease ataxia-telangiectasia (A-T) were classified by means of an assay system that monitors complementation of defects in DNA synthesis. Anomalies in DNA synthesis have been observed previously in A-T cells, both in their failure to inhibit DNA synthesis immedi...

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Autors principals: Murnane, J P, Painter, R B
Format: Artigo
Idioma:Inglês
Publicat: 1982
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC346101/
https://ncbi.nlm.nih.gov/pubmed/6952246
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