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Complementation of the defects of DNA synthesis in irradiated and unirradiated ataxia-telangiectasia cells.

Mutant subtypes in the human genetic disease ataxia-telangiectasia (A-T) were classified by means of an assay system that monitors complementation of defects in DNA synthesis. Anomalies in DNA synthesis have been observed previously in A-T cells, both in their failure to inhibit DNA synthesis immedi...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Murnane, J P, Painter, R B
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6952246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.6.1960
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