A Common Origin for the Bacterial Toxin-Antitoxin Systems parD and ccd, Suggested by Analyses of Toxin/Target and Toxin/Antitoxin Interactions

Bacterial toxin-antitoxin (TA) systems encode two proteins, a potent inhibitor of cell proliferation (toxin) and its specific antidote (antitoxin). Structural data has revealed striking similarities between the two model TA toxins CcdB, a DNA gyrase inhibitor encoded by the ccd system of plasmid F,...

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Hauptverfasser: Smith, Andrew B., López-Villarejo, Juan, Diago-Navarro, Elizabeth, Mitchenall, Lesley A., Barendregt, Arjan, Heck, Albert J., Lemonnier, Marc, Maxwell, Anthony, Díaz-Orejas, Ramón
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460896/
https://ncbi.nlm.nih.gov/pubmed/23029540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046499
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