Does Beta-lactam Pharmacokinetic Variability in Critically Ill Patients Justify Therapeutic Drug Monitoring? A Systematic Review

The pharmacokinetics of beta-lactam antibiotics in intensive care patients may be profoundly altered due to the dynamic, unpredictable pathophysiological changes that occur in critical illness. For many drugs, significant increases in the volume of distribution and/or variability in drug clearance a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sime, Fekade Bruck, Roberts, Michael S, Peake, Sandra L, Lipman, Jeffrey, Roberts, Jason A
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2012
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460787/
https://ncbi.nlm.nih.gov/pubmed/22839761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2110-5820-2-35
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky