Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1–, IL-17–, and G-CSF–dependent manner

Neutropenia is a common side effect of cytotoxic chemotherapy and radiation, increasing the risk of infection in these patients. Here we examined the impact of body temperature on neutrophil recovery in the blood and bone marrow after total body irradiation (TBI). Mice were exposed to either 3 or 6...

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Главные авторы: Capitano, Maegan L., Nemeth, Michael J., Mace, Thomas A., Salisbury-Ruf, Christi, Segal, Brahm H., McCarthy, Philip L., Repasky, Elizabeth A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2012
Предметы:
Hematopoiesis and Stem Cells
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460682/
https://ncbi.nlm.nih.gov/pubmed/22806894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-409805
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