Methylation of Lysine 9 in Histone H3 Directs Alternative Modes of Highly Dynamic Interaction of Heterochromatin Protein hHP1β with the Nucleosome

Binding of heterochromatin protein 1 (HP1) to the histone H3 lysine 9 trimethylation (H3K9me3) mark is a hallmark of establishment and maintenance of heterochromatin. Although genetic and cell biological aspects have been elucidated, the molecular details of HP1 binding to H3K9me3 nucleosomes are un...

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Bibliographic Details
Main Authors: Munari, Francesca, Soeroes, Szabolcs, Zenn, Hans Michael, Schomburg, Adrian, Kost, Nils, Schröder, Sabrina, Klingberg, Rebecca, Rezaei-Ghaleh, Nasrollah, Stützer, Alexandra, Gelato, Kathy Ann, Walla, Peter Jomo, Becker, Stefan, Schwarzer, Dirk, Zimmermann, Bastian, Fischle, Wolfgang, Zweckstetter, Markus
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460472/
https://ncbi.nlm.nih.gov/pubmed/22815475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390849
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