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HP1 Recruits Activity-Dependent Neuroprotective Protein to H3K9me3 Marked Pericentromeric Heterochromatin for Silencing of Major Satellite Repeats

H3 lysine 9 trimethylation (H3K9me3) is a histone posttranslational modification (PTM) that has emerged as hallmark of pericentromeric heterochromatin. This constitutive chromatin domain is composed of repetitive DNA elements, whose transcription is differentially regulated. Mammalian cells contain...

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Bibliographische Detailangaben
Hauptverfasser: Mosch, Kerstin, Franz, Henriette, Soeroes, Szabolcs, Singh, Prim B., Fischle, Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022755/
https://ncbi.nlm.nih.gov/pubmed/21267468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015894
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