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The Increase in O-Linked N-Acetylglucosamine Protein Modification Stimulates Chondrogenic Differentiation Both in Vitro and in Vivo

Insulin is an inducer of chondrocyte hypertrophy and growth plate chondrogenesis, although the specific molecular mechanisms behind these effects are mostly unknown. Our aim was to investigate whether insulin-induced chondrocyte hypertrophy occurs through a modification in the amount of O-linked N-a...

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Detalhes bibliográficos
Main Authors: Andrés-Bergós, Jessica, Tardio, Lidia, Larranaga-Vera, Ane, Gómez, Rodolfo, Herrero-Beaumont, Gabriel, Largo, Raquel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460460/
https://ncbi.nlm.nih.gov/pubmed/22859309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.354241
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