RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis

INTRODUCTION: The receptor activator nuclear factor-kappaB ligand (RANKL) diffuses from articular cartilage to subchondral bone. However, the role of chondrocyte-synthesized RANKL in rheumatoid arthritis-associated juxta-articular bone loss has not yet been explored. This study aimed to determine wh...

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Autors principals: Martínez-Calatrava, Maria J, Prieto-Potín, Ivan, Roman-Blas, Jorge A, Tardio, Lidia, Largo, Raquel, Herrero-Beaumont, Gabriel
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446534/
https://ncbi.nlm.nih.gov/pubmed/22709525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3884
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