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Large Protein Assemblies Formed by Multivalent Interactions between Cadherin23 and Harmonin Suggest a Stable Anchorage Structure at the Tip Link of Stereocilia

Stereocilia tip links of inner ear hair cells are subjected to constant stretching during hair-bundle deflection, and accordingly are well designed to prevent from being broken by mechanical tensions. The roots of tip links, which couple tip links with the cytoskeleton, supposedly play important rol...

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Autori principali: Wu, Lin, Pan, Lifeng, Zhang, Chuchu, Zhang, Mingjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460447/
https://ncbi.nlm.nih.gov/pubmed/22879593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378505
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