An Archaeal Immune System Can Detect Multiple Protospacer Adjacent Motifs (PAMs) to Target Invader DNA

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system provides adaptive and heritable immunity against foreign genetic elements in most archaea and many bacteria. Although this system is widespread and diverse with many subtypes, only a few species have...

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Detalhes bibliográficos
Main Authors: Fischer, Susan, Maier, Lisa-Katharina, Stoll, Britta, Brendel, Jutta, Fischer, Eike, Pfeiffer, Friedhelm, Dyall-Smith, Mike, Marchfelder, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460438/
https://ncbi.nlm.nih.gov/pubmed/22767603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377002
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