A Tropomyosin-2 Mutation Suppresses a Troponin I Myopathy in Drosophila

A suppressor mutation, D53, of the held-up(2) allele of the Drosophila melanogaster Troponin I (wupA) gene is described. D53, a missense mutation, S185F, of the tropomyosin-2, Tm2, gene fully suppresses all the phenotypic effects of held-up(2), including the destructive hypercontraction of the indir...

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Publicado en:	Mol Biol Cell
Autores principales:	Naimi, Benyoussef, Harrison, Andrew, Cummins, Mark, Nongthomba, Upendra, Clark, Samantha, Canal, Inmaculada, Ferrus, Alberto, Sparrow, John C.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Cell Biology 2001
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34603/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.5.1529
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