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A Tropomyosin-2 Mutation Suppresses a Troponin I Myopathy in Drosophila

A suppressor mutation, D53, of the held-up(2) allele of the Drosophila melanogaster Troponin I (wupA) gene is described. D53, a missense mutation, S185F, of the tropomyosin-2, Tm2, gene fully suppresses all the phenotypic effects of held-up(2), including the destructive hypercontraction of the indir...

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Udgivet i:Mol Biol Cell
Principais autores: Naimi, Benyoussef, Harrison, Andrew, Cummins, Mark, Nongthomba, Upendra, Clark, Samantha, Canal, Inmaculada, Ferrus, Alberto, Sparrow, John C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.5.1529
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