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Arachidonic acid metabolism in glutathione-deficient macrophages.

Mouse resident peritoneal macrophages were treated with the glutathione (GSH) synthesis inhibitor buthionine sulfoximine to deplete intracellular GSH. The arachidonic acid metabolites released by the GSH-depleted macrophages in response to a zymosan challenge were analyzed by HPLC. Buthionine sulfox...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Rouzer, C A, Scott, W A, Griffith, O W, Hamill, A L, Cohn, Z A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346027/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6803245/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.5.1621
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