Extensive alternative polyadenylation during zebrafish development

The post-transcriptional fate of messenger RNAs (mRNAs) is largely dictated by their 3′ untranslated regions (3′ UTRs), which are defined by cleavage and polyadenylation (CPA) of pre-mRNAs. We used poly(A)-position profiling by sequencing (3P-seq) to map poly(A) sites at eight developmental stages a...

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Main Authors: Ulitsky, Igor, Shkumatava, Alena, Jan, Calvin H., Subtelny, Alexander O., Koppstein, David, Bell, George W., Sive, Hazel, Bartel, David P.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2012
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460199/
https://ncbi.nlm.nih.gov/pubmed/22722342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.139733.112
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