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RNA ligation via 2'-phosphomonoester, 3'5'-phosphodiester linkage: requirement of 2',3'-cyclic phosphate termini and involvement of a 5'-hydroxyl polynucleotide kinase.

Extracts of wheat germ contain a RNA ligase activity that catalyzes the conversion of linear polyribonucleotides into covalently closed circles. As reported previously, this enzyme joins two ends of a RNA substrate via a 2'-phosphomonoester, 3',5'-phosphodiester linkage. In the present work we provi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Konarska, M, Filipowicz, W, Gross, H J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345996/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6280184/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.5.1474
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