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Automated High-Throughput RNAi Screening in Human Cells Combined with Reporter mRNA Transfection to Identify Novel Regulators of Translation

Proteins that promote angiogenesis, such as vascular endothelial growth factor (VEGF), are major targets for cancer therapy. Accordingly, proteins that specifically activate expression of factors like VEGF are potential alternative therapeutic targets and may help to combat evasive resistance to ang...

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Bibliografiske detaljer
Main Authors: Casanova, Claudia M., Sehr, Peter, Putzker, Kerstin, Hentze, Matthias W., Neumann, Beate, Duncan, Kent E., Thoma, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459937/
https://ncbi.nlm.nih.gov/pubmed/23029333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045943
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