Limited Phenotypic Effects of Selectively Augmenting the SMN Protein in the Neurons of a Mouse Model of Severe Spinal Muscular Atrophy

Eitemau Tebyg

• Reduced Survival of Motor Neuron (SMN) Protein in Motor Neuronal Progenitors Functions Cell Autonomously to Cause Spinal Muscular Atrophy in Model Mice Expressing the Human Centromeric (SMN2) Gene
  gan: Park, Gyu-Hwan, et al.
  Cyhoeddwyd: (2010)
• Motor neuronal repletion of the NMJ organizer, Agrin, modulates the severity of the spinal muscular atrophy disease phenotype in model mice
  gan: Kim, Jeong-Ki, et al.
  Cyhoeddwyd: (2017)
• Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
  gan: Kariya, Shingo, et al.
  Cyhoeddwyd: (2008)
• Spinal Muscular Atrophy: Journeying From Bench to Bedside
  gan: Awano, Tomoyuki, et al.
  Cyhoeddwyd: (2014)
• Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy
  gan: Lutz, Cathleen M., et al.
  Cyhoeddwyd: (2011)