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Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy

Spinal muscular atrophy (SMA) is a common pediatric neuromuscular disorder caused by insufficient levels of the survival of motor neuron (SMN) protein. Studies involving SMA patients and animal models expressing the human SMN2 gene have yielded relatively little information about the earliest cellul...

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Autors principals: Kariya, Shingo, Park, Gyu-Hwan, Maeno-Hikichi, Yuka, Leykekhman, Olga, Lutz, Cathleen, Arkovitz, Marc S., Landmesser, Lynn T., Monani, Umrao R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722888/
https://ncbi.nlm.nih.gov/pubmed/18492800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn156
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