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Enhancing the Prioritization of Disease-Causing Genes through Tissue Specific Protein Interaction Networks
The prioritization of candidate disease-causing genes is a fundamental challenge in the post-genomic era. Current state of the art methods exploit a protein-protein interaction (PPI) network for this task. They are based on the observation that genes causing phenotypically-similar diseases tend to l...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3459874/ https://ncbi.nlm.nih.gov/pubmed/23028288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002690 |
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