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Hydrolysis of human platelet membrane glycoproteins with a Serratia marcescens metalloprotease: Effect on response to thrombin and von Willebrand factor

Metalloproteases from at least two Gram-negative organisms selectively hydrolyze the surface of human fixed washed platelets. The protease-treated platelets lose their ability to aggregate with bovine von Willebrand factor and human von Willebrand factor plus ristocetin. The present study reports th...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Cooper, Herbert A., Bennett, William P., White, Gilbert C., Wagner, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7041120/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.5.1433
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