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Hydrolysis of human platelet membrane glycoproteins with a Serratia marcescens metalloprotease: Effect on response to thrombin and von Willebrand factor

Metalloproteases from at least two Gram-negative organisms selectively hydrolyze the surface of human fixed washed platelets. The protease-treated platelets lose their ability to aggregate with bovine von Willebrand factor and human von Willebrand factor plus ristocetin. The present study reports th...

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Detalhes bibliográficos
Main Authors: Cooper, Herbert A., Bennett, William P., White, Gilbert C., Wagner, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC345987/
https://ncbi.nlm.nih.gov/pubmed/7041120
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