Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell–specific abrogation of the glutamate dehydrogenase

In pancreatic β-cells, glutamate dehydrogenase (GDH) modulates insulin secretion, although its function regarding specific secretagogues is unclear. This study investigated the role of GDH using a β-cell–specific GDH knockout mouse model, called βGlud1(−/−). The absence of GDH in islets isolated fro...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Vetterli, Laurène, Carobbio, Stefania, Pournourmohammadi, Shirin, Martin-del-Rio, Rafael, Skytt, Dorte M., Waagepetersen, Helle S., Tamarit-Rodriguez, Jorge, Maechler, Pierre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2012
Onderwerpen:
Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459861/
https://ncbi.nlm.nih.gov/pubmed/22875990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0676
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items