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Regulation of GAD65 expression by SMAR1 and p53 upon Streptozotocin treatment

BACKGROUND: GAD65 (Glutamic acid decarboxylase 65 KDa isoform) is one of the most important auto-antigens involved in Type 1 diabetes induction. Although it serves as one of the first injury markers of β-islets, the mechanisms governing GAD65 expression remain poorly understood. Since the regulation...

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Detalhes bibliográficos
Main Authors: Singh, Sandeep, Raina, Varsheish, Chavali, Pavithra Lakshminarsimhan, Dubash, Taronish, Kadreppa, Sreenath, Parab, Pradeep, Chattopadhyay, Samit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459802/
https://ncbi.nlm.nih.gov/pubmed/22978699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-28
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