Apamin as a selective blocker of the calcium-dependent potassium channel in neuroblastoma cells: voltage-clamp and biochemical characterization of the toxin receptor.

This paper describes the interaction of apamin, a bee venom neurotoxin, with the mouse neuroblastoma cell membrane. Voltage-clamp analyses have shown that apamin at low concentrations specifically blocks the Ca2+-dependent K+ channel in differentiated neuroblastoma cells. Binding experiments with hi...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hugues, M, Romey, G, Duval, D, Vincent, J P, Lazdunski, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1982
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6122211/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.4.1308
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