Apamin as a selective blocker of the calcium-dependent potassium channel in neuroblastoma cells: voltage-clamp and biochemical characterization of the toxin receptor.

This paper describes the interaction of apamin, a bee venom neurotoxin, with the mouse neuroblastoma cell membrane. Voltage-clamp analyses have shown that apamin at low concentrations specifically blocks the Ca2+-dependent K+ channel in differentiated neuroblastoma cells. Binding experiments with hi...

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Detalhes bibliográficos
Main Authors: Hugues, M, Romey, G, Duval, D, Vincent, J P, Lazdunski, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC345952/
https://ncbi.nlm.nih.gov/pubmed/6122211
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