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Gene dosage and gene expression in the HLA region: Evidence from deletion variants

Among variants selected in a human cell line for nonexpression of a single gene product in the HLA complex, most are single-gene variants, but several have been isolated that are cis-acting and abolish expression of a series of closely linked genes. The two most plausible mechanisms by which such va...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Gladstone, Paul, Fueresz, Lucy, Pious, Donald
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6951171/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.4.1235
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