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Genetically Engineered Mice by Pronuclear DNA microinjection

The generation of transgenic mice by DNA microinjection is a powerful tool to investigate the molecular regulation of gene expression, development, and disease. The power of this technology is that foreign DNA can be introduced into every cell of a developing organism and the phenotypic impact of th...

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Bibliografiske detaljer
Main Authors: DeMayo, Janet L., Wang, Jie, Liang, Dongcai, Zhang, Ruina, DeMayo, Francesco J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459342/
https://ncbi.nlm.nih.gov/pubmed/23024927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470942390.mo110168
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