Association of Xmn I Polymorphism and Hemoglobin E Haplotypes on Postnatal Gamma Globin Gene Expression in Homozygous Hemoglobin E

Background and Objectives. To explore the role of cis-regulatory sequences within the β globin gene cluster at chromosome 11 on human γ globin gene expression related to Hb E allele, we analyze baseline hematological data and Hb F values together with β globin haplotypes in homozygous Hb E. Patients...

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Autores principales: Ekwattanakit, Supachai, Monteerarat, Yuwarat, Riolueang, Suchada, Tachavanich, Kalaya, Viprakasit, Vip
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459260/
https://ncbi.nlm.nih.gov/pubmed/23049556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/528075
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