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Proconvertase proteolytic processing of an enzymatically active myeloperoxidase precursor
Optimal and efficient killing of ingested microbes by human neutrophils is mediated in large part by the action of hypochlorous acid produced by the myeloperoxidase-H(2)O(2)-chloride system in phagosomes. Myeloperoxidase gene transcription is limited to early myeloid precursors in the bone marrow, w...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3459156/ https://ncbi.nlm.nih.gov/pubmed/22902565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.07.013 |
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