Adenosine A(2B) receptor-mediated leukemia inhibitory factor release from astrocytes protects cortical neurons against excitotoxicity

BACKGROUND: Neuroprotective and neurotrophic properties of leukemia inhibitory factor (LIF) have been widely reported. In the central nervous system (CNS), astrocytes are the major source for LIF, expression of which is enhanced following disturbances leading to neuronal damage. How astrocytic LIF e...

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Détails bibliographiques
Auteurs principaux: Moidunny, Shamsudheen, Vinet, Jonathan, Wesseling, Evelyn, Bijzet, Johan, Shieh, Chu-Hsin, van Ijzendoorn, Sven CD, Bezzi, Paola, Boddeke, Hendrikus WGM, Biber, Knut
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458985/
https://ncbi.nlm.nih.gov/pubmed/22894638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-198
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