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The Leukemia-Associated Fusion Protein MN1-TEL Blocks TEL-Specific Recognition Sequences

The leukemia-associated fusion protein MN1-TEL combines the transcription-activating domains of MN1 with the DNA-binding domain of the transcriptional repressor TEL. Quantitative photobleaching experiments revealed that ∼20% of GFP-tagged MN1 and TEL is transiently immobilised, likely due to indirec...

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Autors principals: ter Haar, W. Martijn, Meester-Smoor, Magda A., van Wely, Karel H. M., Schot, Claudia C. M. M., Janssen, Marjolein J. F. W., Geverts, Bart, Bonten, Jacqueline, Grosveld, Gerard C., Houtsmuller, Adriaan B., Zwarthoff, Ellen C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458806/
https://ncbi.nlm.nih.gov/pubmed/23049943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046085
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