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Synthesis and evaluation of new guanidine-thiourea organocatalyst for the nitro-Michael reaction: Theoretical studies on mechanism and enantioselectivity

A new guanidine-thiourea organocatalyst has been developed and applied as bifunctional organocatalyst in the Michael addition reaction of diethyl malonate to trans-β-nitrostyrene. Extensive DFT calculations, including solvent effects and dispersion corrections, as well as ab initio calculations prov...

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Hlavní autoři: Shubina, Tatyana E, Freund, Matthias, Schenker, Sebastian, Clark, Timothy, Tsogoeva, Svetlana B
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458773/
https://ncbi.nlm.nih.gov/pubmed/23019483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.168
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