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A novel asymmetric synthesis of cinacalcet hydrochloride

A novel route to asymmetric synthesis of cinacalcet hydrochloride by the application of (R)-tert-butanesulfinamide and regioselective N-alkylation of the naphthyl ethyl sulfinamide intermediate is described.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Arava, Veera R, Gorentla, Laxminarasimhulu, Dubey, Pramod K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Beilstein-Institut 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458763/
https://ncbi.nlm.nih.gov/pubmed/23019473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.158
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