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A novel asymmetric synthesis of cinacalcet hydrochloride
A novel route to asymmetric synthesis of cinacalcet hydrochloride by the application of (R)-tert-butanesulfinamide and regioselective N-alkylation of the naphthyl ethyl sulfinamide intermediate is described.
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458763/ https://ncbi.nlm.nih.gov/pubmed/23019473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.158 |
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