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Synthesis of diverse indole libraries on polystyrene resin – Scope and limitations of an organometallic reaction on solid supports

The synthesis of diverse substituted indole structures on solid supports is described. The immobilization of nitrobenzoic acid onto Merrifield resin and the subsequent treatment with alkenyl Grignard reagents delivered indole carboxylates bound to solid supports. In contrast to results in the liquid...

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Autors principals: Knepper, Kerstin, Vanderheiden, Sylvia, Bräse, Stefan
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458737/
https://ncbi.nlm.nih.gov/pubmed/23019447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.132
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