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Synthesis of a library of tricyclic azepinoisoindolinones
Hydrozirconation of 1-hexyne, the addition to in situ prepared N-acyliminium species, and ring-closing metathesis (RCM) were key steps in the preparation of a tricyclic isoindolinone scaffold. An unusual alkene isomerization process during the RCM was identified and studied in some detail. Chemical...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458725/ https://ncbi.nlm.nih.gov/pubmed/23019435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.120 |
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