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Fluorous Parallel Synthesis of a Piperazinedione-Fused Tricyclic Compound Library

A fluorous-linker-assisted solution-phase protocol has been developed and applied to parallel synthesis of a piperazinedione-fused tricyclic compound library. The one-pot [3 + 2] cycloaddition of fluorous amino esters, aldehydes, and maleimides afforded bicyclic proline derivatives. The intermediate...

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Bibliografische gegevens
Hoofdauteurs: Werner, Stefan, Nielsen, Simon D., Wipf, Peter, Turner, David M., Chambers, Peter G., Geib, Steven J., Curran, Dennis P., Zhang, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921976/
https://ncbi.nlm.nih.gov/pubmed/19301852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc900003q
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