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Fluorous Parallel Synthesis of a Piperazinedione-Fused Tricyclic Compound Library
A fluorous-linker-assisted solution-phase protocol has been developed and applied to parallel synthesis of a piperazinedione-fused tricyclic compound library. The one-pot [3 + 2] cycloaddition of fluorous amino esters, aldehydes, and maleimides afforded bicyclic proline derivatives. The intermediate...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921976/ https://ncbi.nlm.nih.gov/pubmed/19301852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc900003q |
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